Press Release

SOUTH SAN FRANCISCO, Calif., July 23, 2024 (GLOBE NEWSWIRE) -- Alector, Inc. (Nasdaq: ALEC), a clinical-stage biotechnology company pioneering immuno-neurology, today announced presentations related to the Company’s TREM2 and progranulin programs at the upcoming Alzheimer's Association International Conference^® 2024 (AAIC^®) being held online and in Philadelphia, Pennsylvania from July 28 – August 1, 2024.

Poster presentations will be available for on-demand viewing beginning on July 28 at 8:00 a.m. ET.

AL002 Presentations
TREM2 Program (AL002) is Being Developed in Collaboration with AbbVie

Poster Title: Baseline characteristics for INVOKE-2: a phase 2 randomized, double-blind, placebo-controlled study evaluating AL002 in early Alzheimer’s disease (#95594)
Presenting Author: Arthur J. Mayorga, Ph.D., Vice President, Clinical Development Neurology, Alector
Session Date and Time: Sunday, July 28, 2024 from 8:00 a.m. – 4:15 p.m. ET

Poster Title: Use of a blood-based amyloid test for screening in INVOKE-2: a phase 2 randomized, double-blind, placebo-controlled study evaluating AL002 in early Alzheimer’s disease (#95646)
Presenting Author: Brady Burgess, Ph.D., Staff Scientist, Alector
Session Date and Time: Monday, July 29, 2024 from 8:00 a.m. – 4:15 p.m. ET

Progranulin Presentations
Progranulin Programs (latozinemab (AL001) and AL101/GSK4527226) are Being Developed in Collaboration with GSK

Poster Title: Using plasma biomarkers to distinguish TDP43 associated pathologies (#89291)
Presenting Author: Gopi Ganji, Ph.D., Scientific Leader, GSK
Session Date and Time: Monday, July 29, 2024 from 8:00 a.m. – 4:15 p.m. ET

Poster Title: PROGRESS-AD: a phase 2 study to evaluate efficacy and safety of GSK4527226 (AL101), an anti-sortilin monoclonal antibody, in patients with early Alzheimer's disease (#90247)
Presenting Author: Christine Bailey, Ph.D., Clinical Development Director, GSK
Session Date and Time: Sunday, July 28, 2024 from 8:00 a.m. – 4:15 p.m. ET

Poster Topic: Genetics, progranulin, and Alzheimer’s disease (#89497)
Presenting Author:  Chun-Fand Xu, Ph.D., Senior Director, Human Genetics, GSK
Session Date and Time:  Sunday, July 28, 2024 from 8:00 a.m. – 4:15 p.m. ET

About Alector
Alector is a clinical-stage biotechnology company pioneering immuno-neurology, a novel therapeutic approach for the treatment of neurodegenerative diseases. Immuno-neurology targets immune dysfunction as a root cause of multiple pathologies that are drivers of degenerative brain disorders. Alector has discovered and is developing a broad portfolio of innate immune system programs, designed to functionally repair genetic mutations that cause dysfunction of the brain’s immune system and enable rejuvenated immune cells to counteract emerging brain pathologies. Alector’s immuno-neurology product candidates are supported by biomarkers and seek to treat indications, including Alzheimer’s disease and genetically defined frontotemporal dementia patient populations. Alector is headquartered in South San Francisco, California. For additional information, please visit www.alector.com.

Alector Contacts:

Alector
Katie Hogan
202-549-0557
katie.hogan@alector.com

1AB (media)
Dan Budwick
973-271-6085
dan@1abmedia.com

Argot Partners (investors)
Laura Perry
212.600.1902
alector@argotpartners.com

Source: Alector, Inc.