8-K
false 0001653087 0001653087 2021-09-23 2021-09-23

 

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

 

FORM 8-K

 

 

CURRENT REPORT

Pursuant to Section 13 or 15(d)

of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): September 23, 2021

 

 

Alector, Inc.

(Exact name of Registrant as Specified in Its Charter)

 

 

 

Delaware   001-38792   82-2933343
(State or Other Jurisdiction
of Incorporation)
  (Commission
File Number)
  (IRS Employer
Identification No.)

 

131 Oyster Point Blvd.  
Suite 600  
South San Francisco, California   94080
(Address of Principal Executive Offices)   (Zip Code)

Registrant’s Telephone Number, Including Area Code: (415) 231-5660

Not Applicable

(Former Name or Former Address, if Changed Since Last Report)

 

 

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

 

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

 

Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

 

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

 

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

 

Title of each class

  

Trading
Symbol(s)

  

Name of each exchange
on which registered

Common Stock    ALEC    The NASDAQ Stock Market LLC

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

 

 

 


Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On September 23, 2021, Elizabeth A. Garofalo, M.D. was appointed to the Board of Directors (the “Board”) of Alector, Inc. (the “Company”). Dr. Garofalo will serve as a Class II director, with a term expiring at the Company’s 2023 annual meeting of the stockholders. The Board will determine Dr. Garofalo’s committee assignment at a later date.

Dr. Garofalo, 64, has served as the Principal for EAG Pharma Consulting LLC since 2016. Prior to that, Dr. Garofalo served in numerous leadership roles including as Senior Vice President and Global Head of Clinical Development and member of the Novartis Global Development Leadership Team. In addition, she served as the Chair of the Novartis Portfolio Stewardship Board and Co-Head of the Novartis Neuroscience Franchise. Prior to that, she was Vice President and Head of the Neuroscience Therapy Area at Astellas. She started her career at Parke-Davis/Pfizer where she had jobs of increasing responsibility including Ann Arbor Site Head of Neuroscience and Ann Arbor Site Head of Worldwide Regulatory Affairs. Since September 2020, Dr. Garofalo has served as a member of the board of Acadia Pharmaceuticals Inc. Further, since March 2021, she has served as a member of the board and member of the Audit Committee of Exicure Inc. and since June 2021 as a member of the board of Xenon Pharmaceuticals. She also serves on the board of the Institute for Advanced Clinical Trials in Children and is the Chair of the Business Advisory Board for the Epilepsy Foundation of America. She earned her M.D. from the Indiana University School of Medicine where she completed her pediatric residency. She completed fellowships in pediatric neurology and epilepsy at the University of Michigan Medical School.

Dr. Garofalo will be compensated in accordance with the Company’s Outside Director Compensation Policy for non-employee directors (the “Policy”). Pursuant to the Policy, Dr. Garofalo will be paid $40,000 per fiscal year for her service as a director on the Board, payable quarterly in arrears on a pro-rata basis. On September 23, 2021, Dr. Garofalo was automatically granted an option to purchase 33,235 shares of Alector common stock, which vests as to 25% of the shares on the one-year anniversary of the grant date and as to 1/48th of the shares on each monthly anniversary of the grant date thereafter, provided that she remains a service provider through the applicable vesting date. Such option will become fully vested and exercisable immediately prior to a change in control transaction, subject to Dr. Garofalo continuing to be a service provider through such change in control. Dr. Garofalo will also be reimbursed for out-of-pocket expenses incurred in connection with her attendance at Board meetings.

Dr. Garofalo will be eligible for further equity awards on the same terms as other continuing non-employee members of the Board. Dr. Garofalo also executed the Company’s standard form of indemnification agreement, which is attached as Exhibit 10.1 to the Company’s Registration Statement on Form S-1 filed with the Securities and Exchange Commission on January 7, 2019 (File No. 333-229152).

There is no arrangement or understanding between Dr. Garofalo and any other persons pursuant to which Dr. Garofalo was elected as a director. In addition, Dr. Garofalo is not a party to any transaction, or series of transactions, required to be disclosed pursuant to Item 404(a) of Regulation S-K.

On September 28, 2021, Alector issued a press release announcing Dr. Garofalo’s appointment to the Board. The press release is attached hereto as Exhibit 99.1.

The information included in the press release in Exhibit 99.1 shall not be deemed to be “filed” for the purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of such section, nor shall such information be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act of 1934, as amended.


Item 9.01 Financial Statements and Exhibits.

(d) Exhibits

 

Exhibit No.    Description
99.1    Press Release dated September 28, 2021.
104    Cover Page Interactive Data File (the cover page XBRL tags are embedded within the Inline XBRL document).


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

 

    ALECTOR, INC.
Date: September 28, 2021     By:  

/s/ Arnon Rosenthal

     

Arnon Rosenthal, Ph.D.

Co-founder and Chief Executive Officer

EX-99.1

Exhibit 99.1

 

LOGO

Alector Announces Appointment of Elizabeth A. Garofalo, M.D.,

to its Board of Directors

South San Francisco, Calif., September 28, 2021 — Alector, Inc. (Nasdaq: ALEC), a clinical-stage biotechnology company pioneering immuno-neurology, today announced the addition of Elizabeth (Betsy) A. Garofalo, M.D., to the Company’s Board of Directors. Dr. Garofalo is a veteran biopharmaceutical executive with more than 25 years of experience in global clinical development and regulatory affairs, with a focus on neurology.

“Betsy is a highly-regarded leader with unmatched clinical development experience, particularly in neurodegenerative disease indications. As we advance our pipeline of novel immuno-neurology therapeutics into later-stage clinical trials, her expert perspective in neurology drug development will be a strong and valued addition to our team,” said Arnon Rosenthal, Ph.D., Chief Executive Officer of Alector.

Since 2016, Dr. Garofalo has served as the principal for EAG Pharma Consulting LLC. Previously, Dr. Garofalo worked for Novartis, serving as Senior Vice President and Global Head of Clinical Development and as a member of its Global Development Leadership Team; she was also Chair of the Novartis Portfolio Stewardship Board and Co-Head of the Novartis Neuroscience Franchise. Prior to Novartis, Dr. Garofalo held several leadership positions, including Global Therapeutics Area Leader, CNS at Astellas; Ann Arbor Site Head, Worldwide Regulatory Affairs at Pfizer; and Ann Arbor Site Head of Neuroscience at Pfizer. Dr. Garofalo currently serves on the Boards of Xenon Pharmaceuticals, Inc., Exicure, Inc. and Acadia Pharmaceuticals Inc. She is also Chair of the Pediatric Oversight Committee at the Institute for Advanced Clinical Trials in Children and is the Chair of the Business Advisory Board for the Epilepsy Foundation of America. Dr. Garofalo holds an M.D. from the Indiana University School of Medicine and completed fellowships in pediatric neurology and epilepsy at the University of Michigan Medical School.

“Alector is well-positioned to be a leader in the neurology space, with a promising and productive platform that leverages an understanding of the brain’s immune system and the genetic underpinnings of degenerative diseases to advance clinical programs aimed at addressing significant problems associated with diseases such as frontotemporal dementia, Alzheimer’s, and ALS,” said Dr. Garofalo. “I look forward to working with Arnon, the leadership team and the Board to support the continued growth of Alector’s neurology programs to help make a meaningful difference in the lives of patients.”

About Alector

Alector is a clinical-stage biotechnology company pioneering immuno-neurology, a novel therapeutic approach for the treatment of neurodegenerative diseases. Immuno-neurology targets immune dysfunction as a root cause of multiple pathologies that are drivers of degenerative brain disorders. Alector has discovered and is developing a broad portfolio of innate immune system programs, designed to functionally repair genetic mutations that cause dysfunction of the brain’s immune system and enable the rejuvenated immune cells to counteract emerging brain pathologies. Alector’s immuno-neurology product candidates are supported by biomarkers and target genetically defined patient populations in frontotemporal dementia and Alzheimer’s disease. This scientific approach is also the basis for the company’s immuno-oncology programs. Alector is headquartered in South San Francisco, California. For additional information, please visit www.alector.com.


Alector Contacts

Michelle Corral

VP, Communications and Investor Relations

650-808-7016

michelle.corral@alector.com

1AB (media)

Dan Budwick

973-271-6085

dan@1abmedia.com

Argot Partners (investors)

Laura Perry/Eric Kasper

Argot Partners

212.600.1902

alector@argotpartners.com