February 4, 2019
VIA EDGAR
Securities and Exchange Commission
Division of Corporation Finance
Office of Healthcare & Insurance
100 F Street, N.E.
Washington, DC 20549-3720
| Attention: | J. Nolan McWilliams |
| Keira Nakada |
| Jim Rosenberg |
| Re: | Alector, Inc. Registration Statement on Form S-1 |
| (File No. 333-229152) |
| Acceleration Request |
| Requested Date: | Wednesday, February 6, 2019 | |
| Requested Time: | 4:00 P.M. Eastern Time |
Ladies and Gentlemen:
Pursuant to Rule 461 under the Securities Act of 1933, as amended, Alector, Inc. (the “Company”) hereby requests that the above-referenced Registration Statement on Form S-l (File No. 333-229152) (the “Registration Statement”) be declared effective at the “Requested Date” and “Requested Time” set forth above or at such later time as the Company or its counsel may orally request via telephone call to the staff of the Division of Corporation Finance of the Securities and Exchange Commission. Once the Registration Statement has been declared effective, please orally confirm that event with our counsel, Wilson Sonsini Goodrich & Rosati, P.C., by calling Tony Jeffries at (650) 849-3223.
[Signature page follows]
Sincerely,
ALECTOR, INC.
/s/ Arnon Rosenthal
Arnon Rosenthal, Ph.D.
Chief Executive Officer
Enclosures
| cc (w/o enclosures): | Sabah Oney, Ph.D., Alector, Inc. |
| Stephanie Yonker, Ph.D., Alector, Inc. |
| Tony Jeffries, Wilson Sonsini Goodrich & Rosati, P.C. |
| Michael Coke, Wilson Sonsini Goodrich & Rosati, P.C. |
| Alan F. Denenberg, Davis Polk & Wardwell LLP |
| Stephen Salmon, Davis Polk & Wardwell LLP |