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144: Filer Information

Filer CIK	0001799779
Filer CCC	XXXXXXXX
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer	Alector, Inc.
SEC File Number	001-38792
Address of Issuer	131 Oyster Point Blvd. Suite 600 South San Francisco CALIFORNIA 94080
Phone	(415)-231-5660
Name of Person for Whose Account the Securities are To Be Sold	Gary Romano
See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.
Relationship to Issuer	Officer

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common Stock	E*TRADE Financial Corporation 3 Edison Drive Alpharetta   GA   30005	2567	17533	83351778	06/02/2023	Nasdaq

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common Stock	06/01/2023	Vesting of Restricted Stock Units	Issuer			9358	06/01/2023	(1)

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Name and Address of Seller	Title of Securities Sold	Date of Sale	Amount of Securities Sold	Gross Proceeds
Gary Romano C/O Alector, Inc. 131 Oyster Point Blvd., Suite 600 South San Francisco   CA   94080	Common Stock	03/02/2023	3238	26933

144: Remarks and Signature

Remarks	(1) The securities to be sold were received upon the settlement of vested restricted stock units.
Date of Notice	06/01/2023
ATTENTION:
The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.
Signature	/s/ Jordan Hochstrasser, by power of attorney
ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)

Exhibit 24

POWER OF ATTORNEY

The undersigned reporting person of Alector, Inc., (the “Company”) hereby constitutes and appoints Arnon Rosenthal, Marc Grasso, Cameron Hagen and Jordan Hochstrasser, and each of them, the undersigned’s true and lawful attorney-in-fact to:

1. complete and execute Form 144, Notice of Proposed Sale of Securities, and any other required form, and all amendments to such forms, as such attorney-in-fact shall in his or her discretion determine to be required or advisable pursuant to the Securities Exchange Act of 1933 and the rules and regulations thereunder, or any successor laws and regulations, as a consequence of the undersigned’s disposition of securities of the Company; and

2. do all acts necessary in order to file such forms with the Securities and Exchange Commission, any securities exchange or national association, the Company and such other person or agency as the attorneys-in-fact shall deem appropriate.

The undersigned hereby ratifies and confirms all that said attorneys‑in-fact and agents shall do or cause to be done by virtue hereof. The undersigned acknowledges that the foregoing attorneys-in-fact, in serving in such capacity at the request of the undersigned, are not assuming, nor is the Company assuming, any of the undersigned’s responsibilities to comply with Rule 144 of the Securities Exchange Act of 1933 (as amended).
 

This Power of Attorney shall remain in full force and effect until the undersigned is no longer required to file Form 144 with respect to the undersigned’s disposition of securities issued by the Company, unless earlier revoked by the undersigned in a signed writing delivered to the Company and the foregoing attorneys-in-fact.

IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of this 30th day of May, 2023.

Signature: /s/ Gary Romano

Print Name: Gary Romano